HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Amino-1-(diphenylmethyl)azetidine → 1-(1-Benzhydryl-azetidin-3-ylamino)-3-(2-methyl-benzothiazol-7-yloxy)-propan-2-ol
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-Amino-1-(diphenylmethyl)azetidine | HCID 5744546 | — |
| Edukt | 2-Methyl-7-(oxiranyl-2-ylmethoxy)benzothiazole | HCID 131722120 | — |
| Lösungsmittel | Dioxan ethanol | HCID 22560076 | — |
| Produkt | 1-(1-Benzhydryl-azetidin-3-ylamino)-3-(2-methyl-benzothiazol-7-yloxy)-propan-2-ol | HCID 54077942 | — |
Reaktionsschritte
The title compound was prepared according to Method A from 2-methyl-7-(oxiranyl-2-ylmethoxy)benzothiazole and 3-amino-1-benzhydrylazetidine with dioxane/ethanol (1:1) as the solvent. mp 55° C.; LSIMS m/z 460. The 3-amino-1-benzhydrylazetidine was prepared as described in Preparation 96.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06130217 |
| Quelldatensatz | uspto-grants-2000_10 |
| ORD ID | ord-09b7a2c5efbc48d7901f72b7881882cf |
| Quellennotiz | uspto-grants-2000_10 |