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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 366545Generated: October 30, 2026

5-Nitro-2-oxindole → 5-Amino-2-oxindole

https://huagongshe.com/reaction/366545

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Nitro-2-oxindoleHCID 230366—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
Product5-Amino-2-oxindoleHCID 277321360%

Reaction Steps

5-Nitro-2-oxindole (6.3 9) was hydrogenated in methanol over 10% palladium on carbon to give 3.0 g (60% yield) of the title compound as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06130238
Source datasetuspto-grants-2000_10
ORD IDord-38ccaace6d4e49368c3500e2c8149bea
Source noteuspto-grants-2000_10