HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl 3'-ethoxy-3-nitrobiphenyl-4-malonate → 3'-Ethoxy-3-nitrobiphenyl-4-acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl 3'-ethoxy-3-nitrobiphenyl-4-malonate | HCID 10714380 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 3'-Ethoxy-3-nitrobiphenyl-4-acetic acid | HCID 10780628 | — |
Reaction Steps
Crude dimethyl 3'-ethoxy-3-nitrobiphenyl-4-malonate was heated at 100° C. in 60 mL of 6N hydrochloric acid for 4 days and then cooled. The precipitate was collected by filtration, washed with water and hexane, and dried to give 4.7 g of crude 3'-ethoxy-3-nitrobiphenyl-4-acetic acid as a light tan solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06130238 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-99f5680e8a004edda0f83af679d58da3 |
| Source note | uspto-grants-2000_10 |