HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-(-)-N-Boc-prolinol → tert-butyl (2S)-2-formylpyrrolidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-(-)-N-Boc-prolinol | HCID 643448 | — |
| Reactant | Cbz-L-Prolinol | HCID 11096562 | — |
| Product | tert-butyl (2S)-2-formylpyrrolidine-1-carboxylate | HCID 2734674 | — |
Reaction Steps
(S)-N-Boc-2-Formyl-pyrrolidine was prepared by Swern oxidation of (S)-N-Boc prolinol (Fluka) according to the conditions described by M. G. B. Drew et al., J. Chem. Soc. Perkin 1, 1998, 1627, for the oxidation of CBZ-prolinol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06130239 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-542f8ec3b4d9450a96def8181fc2a8be |
| Source note | uspto-grants-2000_10 |