反应详情

69 g (0.32 mol) of 6-benzyl-octahydropyrrolo[3,4-b]pyridine are hydrogenated in 450 ml of methanol over 7 g of palladium-on-active charcoal (5% strength) at 90° C./90 bar in the course of 3 hours. The catalyst is then filtered off, the filtrate is concentrated and the residue is distilled. 33.8 g (84.% of theory) of a colorless solid having a melting point of 65°-67° C. and a boiling point of 78° C./9 mbar are obtained.

1. customin the course of 3 hours
2. filtrationThe catalyst is then filtered off
3. concentrationthe filtrate is concentrated
4. distillationthe residue is distilled
5. customa boiling point of 78° C./9 mbar are obtained