Benzo-1,3-dioxole-5-methylamine → HCID 178512307, compound

HRID 366792Notes

Reaction equation

HRID 366792 reaction equation
[Cl:1][C:2]1[CH:28]=[CH:27][C:5]2[CH:6]([CH:15]3[CH2:20][CH2:19][N:18]([C:21](SC)=[N:22][C:23]#[N:24])[CH2:17][CH2:16]3)[C:7]3[C:12]([CH2:13][S:14][C:4]=2[CH:3]=1)=[CH:11][CH:10]=[CH:9][N:8]=3.[O:29]1[C:33]2[CH:34]=[CH:35][C:36]([CH2:38][NH2:39])=[CH:37][C:32]=2[O:31][CH2:30]1>>[O:29]1[C:33]2[CH:34]=[CH:35][C:36]([CH2:38][NH:39][C:21]([N:18]3[CH2:19][CH2:20][CH:15]([CH:6]4[C:7]5=[N:8][CH:9]=[CH:10][CH:11]=[C:12]5[CH2:13][S:14][C:4]5[CH:3]=[C:2]([Cl:1])[CH:28]=[CH:27][C:5]4=5)[CH2:16][CH2:17]3)=[N:22][C:23]#[N:24])=[CH:37][C:32]=2[O:31][CH2:30]1

Participants

3

Reactant 2

HCID 75799Benzo-1,3-dioxole-5-methylamineHCID 23289902HCID 23289902, compound

Product 1

HCID 178512307HCID 178512307, compound

Procedure

This compound could be prepared similarly from methyl 4-(8-chloro-5,11-dihydro-[1]benzothiepino[4,3-b]pyridin-11-yl)-N-cyano-1 -piperidine-carboximidothioate and 1,3-benzodioxol-5-ylmethylamine.

Sources & evidence

ORD record
ord-5541ba51bd06411aa31256b2c2753319
Source dataset
uspto-grants-2000_10
Patent number
US06130229

Reaction notes

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