HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl chloroformate → Ethyl 7-benzyl-2,7-diazabicyclo[3.3.0]octane-2-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl chloroformate | HCID 10928 | — |
| Reactant | 5-Benzyl-octahydro-pyrrolo[3,4-b]pyrrole | HCID 15070004 | — |
| Product | Ethyl 7-benzyl-2,7-diazabicyclo[3.3.0]octane-2-carboxylate | HCID 15070027 | — |
Reaction Steps
7-Benzyl-2,7-diazabicyclo[3.3.0]octane (Example Jc) is reacted with ethyl chloroformate analogously to Example Oa) to give ethyl 7-benzyl-2,7-diazabicyclo[3.3.0]octane-2-carboxylate, and this is then debenzylated hydrogenolytically analogously to Example Jd). A colorless oil of boiling point 90° C./0.1 mbar is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05416096 |
| Source dataset | uspto-grants-1995_05 |
| ORD ID | ord-7ef6048260dc41ff871e39a8b0824b2c |
| Source note | uspto-grants-1995_05 |