Benzyl Bromide → HCID 23287622, compound

Participants

Reaction Steps

The reaction procedure of Example 11 was followed except that 901 mg (2.36 mmol) of 2-(4-iodoanilino)-4H-pyrido[3,2-e]-1,3-thiazin-4-one, 23 mg of lithium hydride and 458 mg of benzyl bromide were used. The resulting residue was then purified through silica gel column chromatography (eluant: chloroform) to obtain 678 mg of 3-benzyl-2,3-dihydro-2-[(4-iodophenyl)imino]-4H-pyrido[3,2-e]-1,3-thiazin-4-one (61%, recrystallized from a mixture of ether and hexane).

Provenance & Evidence