Acetone → HCID 941901, compound

Participants

Reaction Steps

The reaction procedure of Example 57 was followed except that 1.757 g (11.2 mmol) of 2-chloronicotinic acid, 15 ml of thionyl chloride, two droplets of DMF, 891 mg of ammonium thiocyanate, 15 ml of acetone, 1.26 g of N-methylaniline and 10 ml of acetone were used. The product was then recrystallized from ethanol to obtain 2.37 g of 2-(N-ethyl-N-phenylamino)-4H-pyrido[3,2-e]-1,3-thiazin-4-one.

Provenance & Evidence