HuagongsheHuagongshe Chemistry Print Report · For research reference only
Indoline → HCID 23287691, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Indoline | HCID 10328 | — |
| Reactant | Ammonium thiocyanate | HCID 15666 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2-Chloronicotinic acid | HCID 76258 | — |
| Solvent | Acetone | HCID 180 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 23287691 | HCID 23287691 | 79.4% |
Reaction Steps
The reaction procedure of Example 57 was followed except that 1.728 mg (10.97 mmol) of 2-chloronicotinic acid, 15 ml of thionyl chloride, two droplets of DMF, 913 mg of ammonium thiocyanate, 15 ml of acetone, 1.31 g of indoline and 10 ml of acetone were used. As a result, 2.45 g of 2-(indolin-1-yl)-4H-pyrido[3,2-e]-1,3-thiazin-4-one was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06133258 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-782d01e554964f3eba8a94e0c4f0bc53 |
| Source note | uspto-grants-2000_10 |