Ammonium thiocyanate → HCID 9840343, compound

Participants

Reaction Steps

The reaction procedure of Example 57 was followed except that 1.585 mg (10.08 mmol) of 2-chloronicotinic acid, 15 ml of thionyl chloride, two droplets of DMF, 844 mg of ammonium thiocyanate, 15 ml of acetone, 1.83 g of N-ethyl-3,4-methylenedioxyaniline and 10 ml of acetone were used. The resulting crude product was then recrystallized from a mixture of ethanol and ether to obtain 1.91 g of 2-[N-ethyl-N-(3,4-methylenedioxyphenyl)amino]-4H-pyrido[3,2-e]-1,3-thiazin-4-one.

Provenance & Evidence