Ammonium thiocyanate → HCID 23287721, compound

Participants

Reaction Steps

The reaction procedure of Example 85 was followed except that 1.891 g (12 mmol) of 2-chloronicotinic acid, 15 ml of thionyl chloride, two droplets of DMF, 960 mg of ammonium thiocyanate, 15 ml of acetone, 1.815 g of 3-methoxy-N-ethylaniline and 10 ml of acetone were used. The resulting crude product was then recrystallized from ethanol to obtain 3.107 g of 2-[N-(3-methoxyphenyl)-N-ethylamino]-4H-pyrido[3,2-e]-1,3-thiazin-4-one.

Provenance & Evidence