反应详情

The reaction procedure of Example 102 was followed except that 1.256 g of 2-chloronicotinoyl chloride, 543 mg of ammonium thiocyanate, 1.379 g of ethyl [4-(methylamino)phenyl]acetate and 24 ml of acetone were used. The product was then recrystallized from ethanol to obtain 1.26 g of ethyl [4-[N-methyl-N-(4-oxo-4H-pyrido[3,2-e]-1,3-thiazin-2-yl)amino]phenyl]acetate.

1. customThe reaction procedure of Example 102
2. customThe product was then recrystallized from ethanol