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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 367225Generated: October 25, 2026

L-Valine → 2-[2-[2-(1-Carboxy-2-methylpropylcarbamoyl) phenyldisulfanyl]benzoylamino]-3-methylbutanoic acid

https://huagongshe.com/reaction/367225

Reaction equation

Participants

RoleNameHCIDCharge
ReactantL-ValineHCID 6287—
Reactant2,2'-Dithiodibenzoyl chlorideHCID 88164—
Product2-[2-[2-(1-Carboxy-2-methylpropylcarbamoyl) phenyldisulfanyl]benzoylamino]-3-methylbutanoic acidHCID 465364—

Reaction Steps

Using the method employed in Preparation 30, 17.8 g (0.15 mol) of D,L valine was reacted with 17.2 g (0.05 mol) of 2,2'-dithiobisbenzoyl chloride to produce 11.4 g of the title compound after recrystallization from acetic acid, mp 226.5-227.5° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06133270
Source datasetuspto-grants-2000_10
ORD IDord-c59ad78ae3394bdbbe3c7de766e63148
Source noteuspto-grants-2000_10