HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → 3-Methyl-2-(3-oxo-2,3-dihydro-1,2-benzothiazol-2-yl)butanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 2-[2-[2-(1-Carboxy-3-methylbutyl carbamoyl)phenyldisulfanyl]benzoylamino)-3-methylbutanoic acid | HCID 53762512 | — |
| Product | 3-Methyl-2-(3-oxo-2,3-dihydro-1,2-benzothiazol-2-yl)butanoic acid | HCID 15410708 | 0.1% |
Reaction Steps
Following the procedure of Example 13, 6.0 g (13.6 mol) of 2-[2-[2-(1-carboxy-3-methylbutyl carbamoyl)phenyldisulfanyl]benzoylamino]-3-methylbutanoic acid was reacted with bromine to provide 2.25 g of the title compound, mp 166-168° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06133270 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-d095c51f5b194452a733e8b25f204107 |
| Source note | uspto-grants-2000_10 |