HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodine → 6-Dimethylamino-2-(2-pyridin-2-yl-ethyl)-isothiazolo[5,4-d]pyrimidin-3-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodine | HCID 807 | — |
| Reactant | HCID 178418253 | HCID 178418253 | — |
| Product | 6-Dimethylamino-2-(2-pyridin-2-yl-ethyl)-isothiazolo[5,4-d]pyrimidin-3-one | HCID 23287888 | 56.3% |
Reaction Steps
Using the procedure of Example 20, 7.5 g (24.8 mmol) of 2-dimethylamino-4-mercapto-pyrimidine-5-carboxylic acid (2-pyridin-2-yl-ethyl)-amide were treated with 6.4 g (25.2 mmol) of iodine to give 4.21 g of the title compound after recrystallization from isopropanol, mp 134-136° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06133270 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-b1ba529ddfc548cdb38ff8e78b1c5333 |
| Source note | uspto-grants-2000_10 |