HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorobenzenesulfonyl chloride → 1-(4-Chlorophenylsulfonyl)-5-fluoro-3-(1-methyl-1,2,3,6-tetrahydro-4-pyridinyl)indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorobenzenesulfonyl chloride | HCID 7398 | — |
| Reactant | 5-fluoro-3-(1-methyl-1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole | HCID 14973209 | — |
| Product | 1-(4-Chlorophenylsulfonyl)-5-fluoro-3-(1-methyl-1,2,3,6-tetrahydro-4-pyridinyl)indole | HCID 23288122 | — |
Reaction Steps
(28.1 mg, 53%), from 5-fluoro-3-(1-methyl-1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole (Example 4b, 30.1 mg, 0.131 mmol) and 4-chlorophenylsulfonyl chloride (55.3 mg, 0.26 mmol); HRMS-FAB+ for C20H19N2O2SClF calculated MH+ : 405.08998; found: 405.08291.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06133287 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-c755d26473024a8dab911e981d5cf944 |
| Source note | uspto-grants-2000_10 |