HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 23288163, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Benzenesulfonyl chloride | HCID 7369 | — |
| Reactant | HCID 3061874 | HCID 3061874 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 23288163 | HCID 23288163 | 76.2% |
Reaction Steps
from 5-chloro-3-(1-methyl-1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole (Example 4d, 25 mg, 0.10 mmol) and phenylsulfonyl chloride (26.4 mg, 0.15 mmol). The HCl salt (29.5 mg, 70%) was prepared from the crude product using 1M HCl in ether; m.p 245-8° C., HRMS-FAB+ for C20H19N2O2SCl.HCl, calculated MH+ (--HCl): 387.09341; found: 387.09262.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06133287 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-1fac4d00994a4d56a352ce1048a26786 |
| Source note | uspto-grants-2000_10 |