HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Naphthalenesulfonyl chloride → HCID 23288160, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Naphthalenesulfonyl chloride | HCID 66560 | — |
| Reactant | Sodium bis(trimethylsilyl)amide | HCID 2724254 | — |
| Reactant | HCID 23288108 | HCID 23288108 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 23288160 | HCID 23288160 | — |
Reaction Steps
(9.2 mg, 52%); from 5,7-difluoro-3-(1-methyl-1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole (Example 4g, 10 mg, 0.04 mmol) and 1-naphthalenesulfonyl chloride (13.6 mg, 0.06 mmol) with 1M NaN(TMS)2 (60 μL, 0.06 mmol) in THF (0.5 mL) at RT.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06133287 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-081131878f8746bda87fafd5df64d362 |
| Source note | uspto-grants-2000_10 |