HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,5-Dichlorobenzoyl chloride → HCID 23288159, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,5-Dichlorobenzoyl chloride | HCID 17945 | — |
| Reactant | Sodium bis(trimethylsilyl)amide | HCID 2724254 | — |
| Reactant | HCID 23288108 | HCID 23288108 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 23288159 | HCID 23288159 | — |
Reaction Steps
(5.6 mg, 33%); from 5,7-difluoro-3-(1-methyl-1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole (Example 4g, 10 mg, 0.04 mmol) and 2,5-dichlorobenzoyl chloride (12.6 mg, 0.06 mmol) with 1M NaN(TMS)2 (60 μL, 0.06 mmol) in THF (0.5 mL) at RT.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06133287 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-23d16c6cb4fa418f90985cc8417356d6 |
| Source note | uspto-grants-2000_10 |