Benzylamine → 2-Chloro-6-ethyl-4-benzylamino-thieno-[2,3-d]-pyrimidine

HRID 367450Notes

Reaction equation

HRID 367450 reaction equation
[CH2:1]([NH2:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Cl:9][C:10]1[N:11]=[C:12](Cl)[C:13]2[CH:18]=[C:17]([CH2:19][CH3:20])[S:16][C:14]=2[N:15]=1>>[Cl:9][C:10]1[N:11]=[C:12]([NH:8][CH2:1][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)[C:13]2[CH:18]=[C:17]([CH2:19][CH3:20])[S:16][C:14]=2[N:15]=1

Participants

3

Reactant 2

HCID 7504BenzylamineHCID 184603242,4-Dichloro-6-ethylthieno[2,3-d]pyrimidine

Product 1

HCID 184604742-Chloro-6-ethyl-4-benzylamino-thieno-[2,3-d]-pyrimidine

Procedure

Following the procedure of Example 1, the reaction of benzylamine with 2,4-dichloro-6-ethyl-thieno-[2,3-d]-pyrimidine yields 2-chloro-6-ethyl-4-benzylamino-thieno-[2,3-d]-pyrimidine.

Sources & evidence

ORD record
ord-c46a5cac2dfb4f6a85438240b5ec3844
Source dataset
uspto-grants-2000_10
Patent number
US06133271

Reaction notes

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