4-Fluorobenzylamine → HCID 18459894, compound

HRID 367457Notes

Reaction equation

HRID 367457 reaction equation
[F:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][NH2:7])=[CH:4][CH:3]=1.[Cl:10][C:11]1[N:12]=[C:13](Cl)[C:14]2[CH:19]=[C:18]([Cl:20])[S:17][C:15]=2[N:16]=1>>[Cl:10][C:11]1[N:12]=[C:13]([NH:7][CH2:6][C:5]2[CH:8]=[CH:9][C:2]([F:1])=[CH:3][CH:4]=2)[C:14]2[CH:19]=[C:18]([Cl:20])[S:17][C:15]=2[N:16]=1

Participants

3

Reactant 2

HCID 673264-FluorobenzylamineHCID 18460009HCID 18460009, compound

Product 1

HCID 18459894HCID 18459894, compound

Procedure

Following the procedure of Example 1, the reaction of 4-fluorobenzylamine with 2,4,6-trichloro-thieno-[2,3-d]-pyrimidine yields 2,6-dichloro-4-(4-fluorobenzylamino)-thieno-[2,3-d]-pyrimidine.

Sources & evidence

ORD record
ord-4bcef5a5277e4df38b00ab31e57e8219
Source dataset
uspto-grants-2000_10
Patent number
US06133271

Reaction notes

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