4-Fluorobenzylamine → HCID 18460270, compound

HRID 367459Notes

Reaction equation

HRID 367459 reaction equation
[F:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][NH2:7])=[CH:4][CH:3]=1.[Cl:10][C:11]1[N:12]=[C:13](Cl)[C:14]2[CH:19]=[C:18]([N+:20]([O-:22])=[O:21])[S:17][C:15]=2[N:16]=1>>[Cl:10][C:11]1[N:12]=[C:13]([NH:7][CH2:6][C:5]2[CH:8]=[CH:9][C:2]([F:1])=[CH:3][CH:4]=2)[C:14]2[CH:19]=[C:18]([N+:20]([O-:22])=[O:21])[S:17][C:15]=2[N:16]=1

Participants

3

Reactant 2

HCID 673264-FluorobenzylamineHCID 18460040HCID 18460040, compound

Product 1

HCID 18460270HCID 18460270, compound

Procedure

Following the procedure of Example 1, the reaction of 4-fluorobenzylamine with 2,4-dichloro-6-nitro-thieno-[2,3-d]-pyrimidine yields 2-chloro-6-nitro-4-(4-fluorobenzylamino)-thieno-[2,3-d]-pyrimidine.

Sources & evidence

ORD record
ord-b6009aa4331744659077d06e57a955a9
Source dataset
uspto-grants-2000_10
Patent number
US06133271

Reaction notes

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