3-Nitrobenzylamine → HCID 18459949, compound

HRID 367472Notes

Reaction equation

HRID 367472 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][CH:11]=1)[CH2:7][NH2:8])([O-:3])=[O:2].[Cl:12][C:13]1[N:14]=[C:15](Cl)[C:16]2[C:21]3[CH2:22][CH2:23][CH2:24][CH2:25][C:20]=3[S:19][C:17]=2[N:18]=1>>[Cl:12][C:13]1[N:14]=[C:15]([NH:8][CH2:7][C:6]2[CH:9]=[CH:10][CH:11]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=2)[C:16]2[C:21]3[CH2:22][CH2:23][CH2:24][CH2:25][C:20]=3[S:19][C:17]=2[N:18]=1

Participants

3

Reactant 2

HCID 1227223-NitrobenzylamineHCID 2902342,4-Dichloro-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidine

Product 1

HCID 18459949HCID 18459949, compound

Procedure

Following the procedure of Example 1, the reaction of 3-nitrobenzylamine with 2,4-dichloro-5,6,7,8-tetrahydro-[1]-benzothieno-[2,3-d]-pyrimidine yields 2-chloro-5,6,7,8-tetrahydro-4-(3-nitrobenzylamino)-[1]-benzothieno-[2,3-d]-pyrimidine.

Sources & evidence

ORD record
ord-0bcf4baa4cfe435190447befc0eeaf41
Source dataset
uspto-grants-2000_10
Patent number
US06133271

Reaction notes

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