Imidazole → HCID 15351971, compound

HRID 367511Notes

Reaction equation

HRID 367511 reaction equation
[NH:1]1[CH:5]=[CH:4][N:3]=[CH:2]1.Cl[C:7]1[N:8]=[C:9]([NH:17][CH2:18][C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[C:10]2[C:15]([CH3:16])=[CH:14][S:13][C:11]=2[N:12]=1>>[N:1]1([C:7]2[N:8]=[C:9]([NH:17][CH2:18][C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[C:10]3[C:15]([CH3:16])=[CH:14][S:13][C:11]=3[N:12]=2)[CH:5]=[CH:4][N:3]=[CH:2]1

Participants

3

Reactant 2

HCID 795ImidazoleHCID 15895117HCID 15895117, compound

Product 1

HCID 15351971HCID 15351971, compound

Procedure

Following the procedure of Example 97, the reaction of imidazole with 2-chloro-5-methyl-4-benzylamino-thieno-[2,3-d]-pyrimidine gives 2-(imidazol-1-yl)-5-methyl-4-benzylamino-thieno-[2,3-d]-pyrimidine.

Sources & evidence

ORD record
ord-7b27c6ea2724465b98e2e150cdcfec7a
Source dataset
uspto-grants-2000_10
Patent number
US06133271

Reaction notes

Loading…