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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 367656Generated: October 28, 2026

1H-1,2,4-Triazole → 2-(1,2,4-Triazol-1-yl)-5-chloro-6-methyl-4-(4-fluorobenzylamino)-thieno-[2,3-d]-pyrimidine

https://huagongshe.com/reaction/367656

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1H-1,2,4-TriazoleHCID 9257—
Reactant2,5-Dichloro-6-methyl-4-(4-fluorobenzylamino)-thieno-[2,3-d]-pyrimidineHCID 18460242—
Product2-(1,2,4-Triazol-1-yl)-5-chloro-6-methyl-4-(4-fluorobenzylamino)-thieno-[2,3-d]-pyrimidineHCID 18459944—

Reaction Steps

Following the procedure of Example 97, the reaction of 1,2,4-triazole with 2,5-dichloro-6-methyl-4-(4-fluorobenzylamino)-thieno-[2,3-d]-pyrimidine gives 2-(1,2,4-triazol-1-yl)-5-chloro-6-methyl-4-(4-fluorobenzylamino)-thieno-[2,3-d]-pyrimidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06133271
Source datasetuspto-grants-2000_10
ORD IDord-727299ede83f4c4b8191df9f094de0c1
Source noteuspto-grants-2000_10