1H-1,2,4-Triazole → HCID 18460027, compound

HRID 367672Notes

Reaction equation

HRID 367672 reaction equation
[NH:1]1[CH:5]=[N:4][CH:3]=[N:2]1.Cl[C:7]1[S:26][C:10]2[N:11]=[CH:12][N:13]=[C:14]([NH:15][CH2:16][C:17]3[CH:22]=[CH:21][CH:20]=[C:19]([N+:23]([O-:25])=[O:24])[CH:18]=3)[C:9]=2[CH:8]=1>>[N:1]1([C:12]2[N:13]=[C:14]([NH:15][CH2:16][C:17]3[CH:22]=[CH:21][CH:20]=[C:19]([N+:23]([O-:25])=[O:24])[CH:18]=3)[C:9]3[CH:8]=[CH:7][S:26][C:10]=3[N:11]=2)[CH:5]=[N:4][CH:3]=[N:2]1

Participants

3

Reactant 2

HCID 92571H-1,2,4-TriazoleHCID 18460468HCID 18460468, compound

Product 1

HCID 18460027HCID 18460027, compound

Procedure

Following the procedure of Example 97, the reaction of 1,2,4-triazole with 6-chloro-4-(3-nitrobenzylamino)-thieno-[2,3-d]-pyrimidine gives 2-(1,2,4-triazol-1-yl)-4-(3-nitrobenzylamino)-thieno-[2,3-d]-pyrimidine.

Sources & evidence

ORD record
ord-2d0733b71f014b44b81a413a80691a4a
Source dataset
uspto-grants-2000_10
Patent number
US06133271

Reaction notes

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