1H-1,2,4-Triazole → HCID 18460200, compound

HRID 367682Notes

Reaction equation

HRID 367682 reaction equation
[NH:1]1[CH:5]=[N:4][CH:3]=[N:2]1.Cl[C:7]1[C:15]2[C:14]([NH:16][CH2:17][CH2:18][C:19]3[CH:24]=[CH:23][C:22]4[O:25][CH2:26][O:27][C:21]=4[CH:20]=3)=[N:13][CH:12]=[N:11][C:10]=2[S:9][C:8]=1[CH3:28]>>[N:1]1([C:12]2[N:13]=[C:14]([NH:16][CH2:17][CH2:18][C:19]3[CH:24]=[CH:23][C:22]4[O:25][CH2:26][O:27][C:21]=4[CH:20]=3)[C:15]3[CH:7]=[C:8]([CH3:28])[S:9][C:10]=3[N:11]=2)[CH:5]=[N:4][CH:3]=[N:2]1

Participants

3

Reactant 2

HCID 92571H-1,2,4-TriazoleHCID 18460058HCID 18460058, compound

Product 1

HCID 18460200HCID 18460200, compound

Procedure

Following the procedure of Example 97, the reaction of 1,2,4-triazole with 5-chloro-6-methyl-4-(3,4-methylenedioxyphenethylamino)-thieno-[2,3-d]-pyrimidine gives 2-(1,2,4-triazol-1-yl)-6-methyl-4-(3,4-methylenedioxyphenethylamino)-thieno-[2,3-d]-pyrimidine.

Sources & evidence

ORD record
ord-4106598682ee4913bea4851ada94a1e8
Source dataset
uspto-grants-2000_10
Patent number
US06133271

Reaction notes

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