2-Methylimidazole → HCID 18460310, compound

HRID 367743Notes

Reaction equation

[CH3:1][C:2]1[NH:3][CH:4]=[CH:5][N:6]=1.Cl[C:8]1[S:27][C:11]2[N:12]=[CH:13][N:14]=[C:15]([NH:16][CH2:17][C:18]3[CH:23]=[CH:22][CH:21]=[C:20]([N+:24]([O-:26])=[O:25])[CH:19]=3)[C:10]=2[CH:9]=1>>[CH3:1][C:2]1[N:3]([C:13]2[N:14]=[C:15]([NH:16][CH2:17][C:18]3[CH:23]=[CH:22][CH:21]=[C:20]([N+:24]([O-:26])=[O:25])[CH:19]=3)[C:10]3[CH:9]=[CH:8][S:27][C:11]=3[N:12]=2)[CH:4]=[CH:5][N:6]=1

Participants

Reactant 2

HCID 127492-Methylimidazole

HCID 18460468HCID 18460468, compound

Product 1

HCID 18460310HCID 18460310, compound

Procedure

Following the procedure of Example 97, the reaction of 2-methylimidazole with 6-chloro-4-(3-nitrobenzylamino)-thieno-[2,3-d]-pyrimidine gives 2-(2-methylimidazol-1-yl)-4-(3-nitrobenzylamino)-thieno-[2,3-d]-pyrimidine.

Sources & evidence

ORD record: ord-758546dd33874156bff53dd5d9d9cee1
Source dataset: uspto-grants-2000_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06133271

Reaction notes

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