2-Methylimidazole → HCID 18460256, compound

HRID 367744Notes

Reaction equation

[CH3:1][C:2]1[NH:3][CH:4]=[CH:5][N:6]=1.Cl[C:8]1[C:16]2[C:15]([NH:17][CH2:18][C:19]3[CH:24]=[CH:23][CH:22]=[C:21]([N+:25]([O-:27])=[O:26])[CH:20]=3)=[N:14][CH:13]=[N:12][C:11]=2[S:10][C:9]=1[CH3:28]>>[CH3:1][C:2]1[N:3]([C:13]2[N:14]=[C:15]([NH:17][CH2:18][C:19]3[CH:24]=[CH:23][CH:22]=[C:21]([N+:25]([O-:27])=[O:26])[CH:20]=3)[C:16]3[CH:8]=[C:9]([CH3:28])[S:10][C:11]=3[N:12]=2)[CH:4]=[CH:5][N:6]=1

Participants

Reactant 2

HCID 127492-Methylimidazole

HCID 18460328HCID 18460328, compound

Product 1

HCID 18460256HCID 18460256, compound

Procedure

Following the procedure of Example 97, the reaction of 2-methylimidazole with 5-chloro-6-methyl-4-(3-nitrobenzylamino)-thieno-[2,3-d]-pyrimidine gives 2-(2-methylimidazol-1-yl)-6-methyl-4-(3-nitrobenzylamino)-thieno-[2,3-d]-pyrimidine.

Sources & evidence

ORD record: ord-283c2ca93e8843adb625de0e502a6f33
Source dataset: uspto-grants-2000_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06133271

Reaction notes

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