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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 367769Generated: October 30, 2026

3-Cyanopyridine → HCID 18460129, compound

https://huagongshe.com/reaction/367769

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-CyanopyridineHCID 79—
ReactantPhosphorus oxychlorideHCID 24813—
ReactantHCID 18459926HCID 18459926—
ProductHCID 18460129HCID 18460129—

Reaction Steps

With the procedure of Example 477, the reaction of 3-cyanopyridine and 2-amino-4-chloro-5-methyl-3-ethoxycarbonyl-thiophene, and the subsequent reaction with POCl3 yields 4-chloro-2-(pyridin-3-yl)-5-chloro-6-methyl-thieno-[2,3-d]-pyrimidine

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06133271
Source datasetuspto-grants-2000_10
ORD IDord-6489dca9aeaa4b5ea49a1fb4680a679a
Source noteuspto-grants-2000_10