Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 367790Generated: October 25, 2026

Pyridine-2-carbonitrile → HCID 18460061, compound

https://huagongshe.com/reaction/367790

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyridine-2-carbonitrileHCID 7522—
ReactantPhosphorus oxychlorideHCID 24813—
ReactantEthyl 2-amino-4,5-dimethyl3-thenoateHCID 78536—
ProductHCID 18460061HCID 18460061—

Reaction Steps

With the procedure of Example 477, the reaction of 2-cyanopyridine and 2-amino-4,5-dimethyl-3-ethoxycarbonyl-thiophene, and the subsequent reaction with POCl3 yields 4-chloro-2-(pyridin-2-yl)-5,6-dimethyl-thieno-[2,3-d]-pyrimidine

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06133271
Source datasetuspto-grants-2000_10
ORD IDord-15a60684f284494ca7cc9908012a4cbf
Source noteuspto-grants-2000_10