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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 367882Generated: October 28, 2026

4-Fluorobenzylamine → 2-(Pyrazin-2-yl)-4-(4-fluorobenzylamino)-5-methyl-thieno-[2,3-d]-pyrimidine

https://huagongshe.com/reaction/367882

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-FluorobenzylamineHCID 67326—
Reactant4-Chloro-2-(pyrazin-2-yl)-5-methyl-thieno-[2,3-d]-pyrimidineHCID 18460114—
Product2-(Pyrazin-2-yl)-4-(4-fluorobenzylamino)-5-methyl-thieno-[2,3-d]-pyrimidineHCID 18460295—

Reaction Steps

With the procedure of Example 1, the reaction of 4-fluorobenzylamine with 4-chloro-2-(pyrazin-2-yl)-5-methyl-thieno-[2,3-d]-pyrimidine yields 2-(pyrazin-2-yl)-4-(4-fluorobenzylamino)-5-methyl-thieno-[2,3-d]-pyrimidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06133271
Source datasetuspto-grants-2000_10
ORD IDord-ef53baa330314417ba428697ff14bb7e
Source noteuspto-grants-2000_10