Benzenemethanamine, 3,4-dichloro- → HCID 18459966, compound

HRID 367963Notes

Reaction equation

HRID 367963 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[Cl:10])[CH2:5][NH2:6].Cl[C:12]1[C:13]2[C:26]([CH3:27])=[CH:25][S:24][C:14]=2[N:15]=[C:16]([C:18]2[CH:23]=[CH:22][N:21]=[CH:20][CH:19]=2)[N:17]=1>>[N:21]1[CH:20]=[CH:19][C:18]([C:16]2[N:17]=[C:12]([NH:6][CH2:5][C:4]3[CH:7]=[CH:8][C:9]([Cl:10])=[C:2]([Cl:1])[CH:3]=3)[C:13]3[C:26]([CH3:27])=[CH:25][S:24][C:14]=3[N:15]=2)=[CH:23][CH:22]=1

Participants

3

Reactant 2

HCID 1608Benzenemethanamine, 3,4-dichloro-HCID 184598924-Chloro-2-(pyridin-4-yl)-5-methyl-thieno-[2,3-d]-pyrimidine

Product 1

HCID 18459966HCID 18459966, compound

Procedure

With the procedure of Example 1, the reaction of 3,4-dichlorobenzylamine with 4-chloro-2-(pyridin-4-yl)-5-methyl-thieno-[2,3-d]-pyrimidine yields 2-(pyridin-4-yl)-4-(3,4-dichlorobenzylamino)-5-methyl-thieno-[2,3-d]-pyrimidine.

Sources & evidence

ORD record
ord-33e1614ec22f49759b7aec89ae2daa6b
Source dataset
uspto-grants-2000_10
Patent number
US06133271

Reaction notes

Loading…