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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 368122Generated: October 30, 2026

1,3-Benzodioxole-5-ethanamine → 2-(Pyrazin-2-yl)-4-(3,4-methylenedioxyphenethylamino)-6-chloro-thieno-[2,3-d]-pyrimidine

https://huagongshe.com/reaction/368122

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-Benzodioxole-5-ethanamineHCID 73874—
Reactant4-Chloro-2-(pyrazin-2-yl)-6-chloro-thieno-[2,3-d]-pyrimidineHCID 18460109—
Product2-(Pyrazin-2-yl)-4-(3,4-methylenedioxyphenethylamino)-6-chloro-thieno-[2,3-d]-pyrimidineHCID 18460516—

Reaction Steps

With the procedure of Example 1, the reaction of 3,4-methylenedioxyphenethylamine with 4-chloro-2-(pyrazin-2-yl)-6-chloro-thieno-[2,3-d]-pyrimidine yields 2-(pyrazin-2-yl)-4-(3,4-methylenedioxyphenethylamino)-6-chloro-thieno-[2,3-d]-pyrimidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06133271
Source datasetuspto-grants-2000_10
ORD IDord-0788fc7d88d84ccba89d697b658fc023
Source noteuspto-grants-2000_10