4-Chloro-2-(pyridin-3-yl)-5-methyl-thieno-[2,3-d]-pyrimidine → HCID 18460003, compound

HRID 368141Notes

Reaction equation

HRID 368141 reaction equation
F[C:2]12[O:14][CH2:13][CH2:12][O:11][CH:3]1[CH:4]=[C:5]([CH:9]=[CH:10]2)[CH2:6][CH2:7][NH2:8].Cl[C:16]1[C:17]2[C:30]([CH3:31])=[CH:29][S:28][C:18]=2[N:19]=[C:20]([C:22]2[CH:23]=[N:24][CH:25]=[CH:26][CH:27]=2)[N:21]=1>>[N:24]1[CH:25]=[CH:26][CH:27]=[C:22]([C:20]2[N:21]=[C:16]([NH:8][CH2:7][CH2:6][C:5]3[CH:9]=[CH:10][C:2]4[O:14][CH2:13][CH2:12][O:11][C:3]=4[CH:4]=3)[C:17]3[C:30]([CH3:31])=[CH:29][S:28][C:18]=3[N:19]=2)[CH:23]=1

Participants

3

Reactant 2

HCID 184600144-Chloro-2-(pyridin-3-yl)-5-methyl-thieno-[2,3-d]-pyrimidineHCID 70145700HCID 70145700, compound

Product 1

HCID 18460003HCID 18460003, compound

Procedure

With the procedure of Example 1, the reaction of 4-fluoro-3,4-ethylenedioxyphenethylamine with 4-chloro-2-(pyridin-3-yl)-5-methyl-thieno-[2,3-d]-pyrimidine yields 2-(pyridin-3-yl)-4-(3,4-ethylenedioxyphenethylamino)-5-methyl-thieno-[2,3-d]-pyrimidine.

Sources & evidence

ORD record
ord-11a2b8c706194163a0e566723081d267
Source dataset
uspto-grants-2000_10
Patent number
US06133271

Reaction notes

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