2-(2,3-Dihydro-1,4-benzodioxin-6-yl)ethan-1-amine → HCID 18460135, compound

HRID 368206Notes

Reaction equation

HRID 368206 reaction equation
[CH2:1]1[CH2:13][O:12][C:11]2[CH:10]=[CH:9][C:5]([CH2:6][CH2:7][NH2:8])=[CH:4][C:3]=2[O:2]1.Cl[C:15]1[C:16]2[CH:29]=[C:28]([Cl:30])[S:27][C:17]=2[N:18]=[C:19]([C:21]2[CH:26]=[CH:25][N:24]=[CH:23][CH:22]=2)[N:20]=1>>[N:24]1[CH:23]=[CH:22][C:21]([C:19]2[N:20]=[C:15]([NH:8][CH2:7][CH2:6][C:5]3[CH:9]=[CH:10][C:11]4[O:12][CH2:13][CH2:1][O:2][C:3]=4[CH:4]=3)[C:16]3[CH:29]=[C:28]([Cl:30])[S:27][C:17]=3[N:18]=2)=[CH:26][CH:25]=1

Participants

3

Reactant 2

HCID 37470272-(2,3-Dihydro-1,4-benzodioxin-6-yl)ethan-1-amineHCID 184599134-Chloro-2-(pyridin-4-yl)-6-chloro-thieno-[2,3-d]-pyrimidine

Product 1

HCID 18460135HCID 18460135, compound

Procedure

With the procedure of Example 1, the reaction of 3,4-ethylenedioxyphenethylamine with 4-chloro-2-(pyridin-4-yl)-6-chloro-thieno-[2,3-d]-pyrimidine yields 2-(pyridin-4-yl)-4-(3,4-ethylenedioxyphenethylamino)-6-chloro-thieno-[2,3-d]-pyrimidine.

Sources & evidence

ORD record
ord-38ffa70e26754255996785bea69d15b1
Source dataset
uspto-grants-2000_10
Patent number
US06133271

Reaction notes

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