Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Aminopyridine → 1-(2,6-Dichlorophenyl)-3-(4-pyridyl)urea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Aminopyridine | HCID 1727 | — |
| 반응물 | 1,3-Dichloro-2-isocyanatobenzene | HCID 604537 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 1-(2,6-Dichlorophenyl)-3-(4-pyridyl)urea | HCID 4610560 | — |
반응 단계
A solution of 4.7 g (0.05 mol) of 4-aminopyridine in 300 mL of anhydrous tetrahydrofuran was treated with 9.4 g (0.05 mol) of 2,6-dichlorophenylisocyanate. The solution was heated at reflux for 24 hours, cooled, and concentrated in vacuo to a solid. Recrystallization from aqueous ethanol afforded the crystalline product, mp 217-219° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06133299 |
| 출처 데이터셋 | uspto-grants-2000_10 |
| ORD ID | ord-3bfc791bba3b426ebce9e41954e978a1 |
| 출처 메모 | uspto-grants-2000_10 |