HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methoxybenzaldehyde → HCID 53682262, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methoxybenzaldehyde | HCID 31244 | — |
| Reactant | 6-(2-Imidazole-1-yl-ethoxy)-3,4-dihydro-2H-naphthalen-1-one | HCID 15486912 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Potassium Hydroxide | HCID 14797 | — |
| Product | HCID 53682262 | HCID 53682262 | 84.9% |
Reaction Steps
According to the method of Example 4, 6-(2-imidazole-1-yl-ethoxy)-3,4-dihydro-2H-naphthalen-1-one (0.200 g, 0.78 mmol) was reacted with p-anisaldehyde (0.117 g, 0.87 mmol) in 2 mL of 4% KOH in EtOH at room temperature overnight to afford 0.248 g (84%) of the title compound, mp 132-133° C.: APCI-MS m/e 375 (M+ +1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06133303 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-473cad85abef4883b7fe708e35170a28 |
| Source note | uspto-grants-2000_10 |