反应详情

To 20 ml of acetonitrile were added 6.0 g of 2,3,5,6-tetrafluoropyridine and 6.0 g of isopropylamine, and the mixture was stirred at room temperature for 2 hours and concentrated under reduced pressure. After adding 40 ml of chloroform, the solution was washed with 50 ml of 3% aqueous solution of potassium carbonate. The chloroform layer was dried over anhydrous magnesium sulfate and concentrated under reduced pressure to obtain 1.9 g of the title compound as a colorless oil.

1. concentrationconcentrated under reduced pressure
2. additionAfter adding 40 ml of chloroform
3. washthe solution was washed with 50 ml of 3% aqueous solution of potassium carbonate
4. dry with materialThe chloroform layer was dried over anhydrous magnesium sulfate
5. concentrationconcentrated under reduced pressure