HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethoxyethylamine → N-(2-ethoxyethyl)-2-chloro-6-(trimethylsilyl)benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethoxyethylamine | HCID 66970 | — |
| Reactant | 2-Chloro-6-(trimethylsilyl)benzoyl chloride | HCID 15183557 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | N-(2-ethoxyethyl)-2-chloro-6-(trimethylsilyl)benzamide | HCID 18630026 | 66.2% |
Reaction Steps
The compound of Example b (4.94 g, 20 mmol), 2-ethoxyethyl amine (3.92 g, 44 mmol), and toluene (35 mL) were combined according to General Method E1. The crude product was recrystallized from aq ethanol to afford 3.97 g of N-(2-ethoxyethyl)-2-chloro-6-(trimethylsilyl)benzamide as white solid, a 66% yield. m.p. 71-73° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06133252 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-7c7469ef38f34e528b1eecd2407de8d7 |
| Source note | uspto-grants-2000_10 |