Aniline → HCID 23288693, compound

HRID 368754Notes

Reaction equation

[Cl:1][C:2]1[CH:35]=[CH:34][C:33]([O:36][CH3:37])=[CH:32][C:3]=1[O:4][C:5]1[C:13]([NH:14][S:15]([C:18]2[CH:23]=[CH:22][C:21]([C:24]([F:27])([F:26])[F:25])=[CH:20][CH:19]=2)(=[O:17])=[O:16])=[CH:12][C:8]([C:9]([OH:11])=O)=[CH:7][C:6]=1[O:28][CH2:29][CH2:30][OH:31].[NH2:38][C:39]1[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=1>>[Cl:1][C:2]1[CH:35]=[CH:34][C:33]([O:36][CH3:37])=[CH:32][C:3]=1[O:4][C:5]1[C:13]([NH:14][S:15]([C:18]2[CH:23]=[CH:22][C:21]([C:24]([F:26])([F:25])[F:27])=[CH:20][CH:19]=2)(=[O:16])=[O:17])=[CH:12][C:8]([C:9]([NH:38][C:39]2[CH:44]=[CH:43][CH:42]=[CH:41][CH:40]=2)=[O:11])=[CH:7][C:6]=1[O:28][CH2:29][CH2:30][OH:31]

Participants

Reactant 2

HCID 6115Aniline

HCID 17878655HCID 17878655, compound

Product 1

HCID 23288693HCID 23288693, compound

Procedure

Analogously to Example 74, by condensing 4-(2-chloro-5-methoxy-phenoxy)-3-(2-hydroxy-ethoxy)-5-(4-trifluoromethyl-benzenesulphonylamino)-benzoic acid with aniline there was obtained 4-(2-chloro-5-methoxy-phenoxy)-3-(2-hydroxy-ethoxy)-N-phenyl-5-(4-trifluoromethyl-benzenesulphonylamino)-benzamide.

Sources & evidence

ORD record: ord-bdf9ce727b084636a7b0e937e328856c
Source dataset: uspto-grants-2000_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06133442

Reaction notes

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