2-Aminobiphenyl → HCID 23288702, compound

HRID 368759Notes

Reaction equation

HRID 368759 reaction equation
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([S:11]([NH:14][C:15]2[CH:16]=[C:17]([CH:21]=[C:22]([O:33][CH2:34][CH2:35][OH:36])[C:23]=2[O:24][C:25]2[CH:30]=[CH:29][CH:28]=[C:27]([O:31][CH3:32])[CH:26]=2)[C:18](O)=[O:19])(=[O:13])=[O:12])=[CH:7][CH:6]=1)([CH3:4])([CH3:3])[CH3:2].[NH2:37][C:38]1[CH:43]=[CH:42][CH:41]=[CH:40][C:39]=1[C:44]1[CH:49]=[CH:48][CH:47]=[CH:46][CH:45]=1>>[C:39]1([C:44]2[CH:45]=[CH:46][CH:47]=[CH:48][CH:49]=2)[CH:40]=[CH:41][CH:42]=[CH:43][C:38]=1[NH:37][C:18](=[O:19])[C:17]1[CH:21]=[C:22]([O:33][CH2:34][CH2:35][OH:36])[C:23]([O:24][C:25]2[CH:30]=[CH:29][CH:28]=[C:27]([O:31][CH3:32])[CH:26]=2)=[C:15]([NH:14][S:11]([C:8]2[CH:7]=[CH:6][C:5]([C:1]([CH3:3])([CH3:2])[CH3:4])=[CH:10][CH:9]=2)(=[O:13])=[O:12])[CH:16]=1

Participants

3

Reactant 2

HCID 70152-AminobiphenylHCID 17878578HCID 17878578, compound

Product 1

HCID 23288702HCID 23288702, compound

Procedure

Analogously to Example 74, by condensing 3-(4-tert-butyl-benzenesulphonylamino)-5-(2-hydroxy-ethoxy)-4-(3-methoxy-phenoxy)-benzoic acid with 2-aminobiphenyl there was obtained N-biphenyl-2-yl-3-(4-tert-butyl-benzenesulphonylamino)-5-(2-hydroxy-ethoxy)-4-(3-methoxy-phenoxy)-benzamide.

Sources & evidence

ORD record
ord-cf749e4b25414804be9ed8841c6e292d
Source dataset
uspto-grants-2000_10
Patent number
US06133442

Reaction notes

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