HRID368767

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6115

Aniline

C6H7N

结构：COc1ccc(S(=O)(=O)Nc2cc(C(=O)O)cc(OCC(O)CO)c2Oc2cccc(OC)c2)cc1

HCID17878619

未命名化合物

PRODUCTS

生成物

结构：COc1ccc(S(=O)(=O)Nc2cc(C(=O)Nc3ccccc3)cc(OCC(O)CO)c2Oc2cccc(OC)c2)cc1

HCID23288643

未命名化合物

PROCEDURE

实验过程

In analogy to Example 121, by coupling 3-(2,3-dihydroxy-propoxy)-5-(4-methoxy-benzenesulphonylamino)-4-(3-methoxy-phenoxy)-benzoic acid with aniline there was obtained 3-(2,3-dihydroxy-propoxy)-5-(4-methoxy-benzenesulphonylamino)-4-(3-methoxy-phenoxy)-N-phenyl-benzamide as a foam.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-5703e4cc066f446496ad6dbdd838c975
来源数据集: uspto-grants-2000_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06133442
来源说明: uspto-grants-2000_10

反应 SMILES

[OH:1][CH:2]([CH2:35][OH:36])[CH2:3][O:4][C:5]1[CH:6]=[C:7]([CH:11]=[C:12]([NH:23][S:24]([C:27]2[CH:32]=[CH:31][C:30]([O:33][CH3:34])=[CH:29][CH:28]=2)(=[O:26])=[O:25])[C:13]=1[O:14][C:15]1[CH:20]=[CH:19][CH:18]=[C:17]([O:21][CH3:22])[CH:16]=1)[C:8](O)=[O:9].[NH2:37][C:38]1[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=1>>[OH:1][CH:2]([CH2:35][OH:36])[CH2:3][O:4][C:5]1[CH:6]=[C:7]([CH:11]=[C:12]([NH:23][S:24]([C:27]2[CH:28]=[CH:29][C:30]([O:33][CH3:34])=[CH:31][CH:32]=2)(=[O:26])=[O:25])[C:13]=1[O:14][C:15]1[CH:20]=[CH:19][CH:18]=[C:17]([O:21][CH3:22])[CH:16]=1)[C:8]([NH:37][C:38]1[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=1)=[O:9]