HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → 2-Bromo-3-chlorobenzyl bromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | Hydrogen Peroxide | HCID 784 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Azobisisobutyronitrile | HCID 6547 | — |
| Reactant | 2-Bromo-1-chloro-3-methylbenzene | HCID 2735553 | — |
| Solvent | Chlorobenzene | HCID 7964 | — |
| Product | 2-Bromo-3-chlorobenzyl bromide | HCID 23289004 | — |
Reaction Steps
267.7 g of 2-bromo-3-chlorotoluene, 530 g of chlorobenzene, 2.5 g of conc. H2SO4, 257.9 g of 47% strength hydrobromic acid and 14 g of 2,2'-azobis(2-methylpropionitrile) were mixed at 63° C. in a 2 l stirred apparatus. 332.3 g of a 10% strength aqueous hydrogen peroxide solution were added dropwise over the course of one hour and 25 minutes, and then the mixture was stirred at 63° C. for 30 minutes. GC analysis of the org. phase:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06133468 |
| Source dataset | uspto-grants-2000_10 |
| ORD ID | ord-d6f531872e1945dba343cb1077c4411b |
| Source note | uspto-grants-2000_10 |