4-(Methylsulfonyl)phenylhydrazine hydrochloride → HCID 23285357, compound

HRID 369098Notes

Reaction equation

HRID 369098 reaction equation
[CH3:1][C:2]1[CH:22]=[CH:21][C:5]2[N:6]=[C:7]([C:9](=O)[CH2:10][C:11](=O)[C:12]([F:18])([F:17])[C:13]([F:16])([F:15])[F:14])[S:8][C:4]=2[CH:3]=1.Cl.[CH3:24][S:25]([C:28]1[CH:33]=[CH:32][C:31]([NH:34][NH2:35])=[CH:30][CH:29]=1)(=[O:27])=[O:26]>>[CH3:1][C:2]1[CH:22]=[CH:21][C:5]2[N:6]=[C:7]([C:9]3[N:34]([C:31]4[CH:30]=[CH:29][C:28]([S:25]([CH3:24])(=[O:27])=[O:26])=[CH:33][CH:32]=4)[N:35]=[C:11]([C:12]([F:18])([F:17])[C:13]([F:16])([F:15])[F:14])[CH:10]=3)[S:8][C:4]=2[CH:3]=1

Participants

3

Reactant 2

HCID 27351814-(Methylsulfonyl)phenylhydrazine hydrochlorideHCID 23285381HCID 23285381, compound

Product 1

HCID 23285357HCID 23285357, compoundYield 45%

Procedure

The procedure of Example 9 was repeated using 1-(6-methylbenzothiazol-2-yl)-4,4,5,5,5-pentafluoropentane-1,3-dione and 4-methylsulfonylphenylhydrazine hydrochloride as the starting materials to obtain 6-methyl-2-[1-(4-methylsulfonylphenyl)-3-pentafluoroethyl-1H-pyrazol-5-yl]benzothiazole (yield, 45%).

Sources & evidence

ORD record
ord-9aceb9f0094c402fad4085532d07d849
Source dataset
uspto-grants-2000_10
Patent number
US06136831

Reaction notes

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