Hydrochloric Acid → HCID 23284750, compound

Participants

Reaction Steps

12N Hydrochloric acid (4 ml) was added to ethyl 1-[5-(N-tert-butoxycarbonyl-N-methylamino)-2,4-difluorophenyl]-6,7-difluoro-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylate (400 mg), and the mixture was stirred for 3 days while heating under reflux. After the reaction mixture was allowed to cool, solids were collected by filtration, washed with ethanol and dried to obtain the title compound (240 mg) as a colorless powder.

Provenance & Evidence