反应详情

Methyl 2-[2-benzyloxy-5-(2-methyl-1,3-dioxolan-2-yl)phenyl]acetate (9.0 g) was dissolved in diethyl ether (130 ml), and lithium aluminum hydride (1.0 g) was added portionwise to the solution under ice-cooling with stirring. After reaction for an hour, water was added portionwise to the reaction mixture under ice-cooling with stirring, and the resulting precipitates were filtered off. Concentration of the filtrate in vacuo gave 2-[2-benzyloxy-5-(2-methyl-1,3-dioxolan-2-yl)phenyl]ethanol (9.0 g) as an oil.

1. temperaturecooling
2. customAfter reaction for an hour
3. temperaturecooling
4. stirringwith stirring
5. customthe resulting precipitates
6. filtrationwere filtered off