1-Bromo-3-chloropropane → HCID 23286062, compound

Participants

Reaction Conditions

Reaction Steps

6-Ethoxycarbonyl-3-hydroxyflavone (3.2 mmol), 1-bromo-3-chloropropane (3.2 mmol) and potassium carbonate (3.2 mmol) were dissolved in 20 ml of DMF, followed by stirring at 100° C. for 2 hours. The reaction mixture was concentrated under reduced pressure. Chloroform was added to the residue, and an insoluble mater was removed. The filtrate was concentrated under reduced pressure. The residue was purified by chromatography on a silica gel column (petroleum ether:ethyl acetate=2:1), whereby the title compound represented by the following formula was obtained as a colorless oil (yield: 38%). ##STR61##

Provenance & Evidence