3-Butyn-1-OL → HCID 86755959, compound

HRID 369472Notes

Reaction equation

HRID 369472 reaction equation
I[C:2]1[N:3]([CH2:16][C:17]2[C:26]3[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=3)[CH:20]=[CH:19][CH:18]=2)[CH:4]=[C:5]2[C:10]=1[CH2:9][N:8]([CH3:11])[CH2:7][N:6]2[CH2:12][CH:13]([CH3:15])[CH3:14].[CH2:27]([OH:31])[CH2:28][C:29]#[CH:30]>>[OH:31][CH2:27][CH2:28][C:29]#[C:30][C:2]1[N:3]([CH2:16][C:17]2[C:26]3[C:21](=[CH:22][CH:23]=[CH:24][CH:25]=3)[CH:20]=[CH:19][CH:18]=2)[CH:4]=[C:5]2[C:10]=1[CH2:9][N:8]([CH3:11])[CH2:7][N:6]2[CH2:12][CH:13]([CH3:14])[CH3:15]

Participants

3

Reactant 2

HCID 135663-Butyn-1-OLHCID 86755960HCID 86755960, compound

Product 1

HCID 86755959HCID 86755959, compound

Procedure

The title compound was prepared from 5-iodo-3-methyl-1-(2-methylpropyl)-6-(1-naphthalenylmethyl )-1 H -pyrrolo[3,4-d]pyrimidine-2,4(3 H, 6 H)-dione and 3-butyn-1-ol in a manner analogous to the method of Example 13 above.

Sources & evidence

ORD record
ord-cc9589b02403449aa1e4ff378b2cbcf2
Source dataset
uspto-grants-2000_10
Patent number
US06136974

Reaction notes

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